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Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone
Specifications
| Product Data |
| Product Name |
Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone |
| Type |
Human Tagged ORF Clone |
| Tag |
TurboGFP |
| Symbol |
CA9 |
| Synonyms |
CAIX; MN |
| Vector |
pCMV6-AC-GFP |
| E. coli Selection |
Ampicillin (100 ug/mL) |
| Cell Selection |
Neomycin |
| Sequence Data |
|
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene Plasmid Map  |
| Tag |
TurboGFP |
| ACCN |
NM_001216 |
| ORF Size |
1377 bp |
| OTI Disclaimer |
The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation |
This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components |
The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers. |
| Reference Data |
| RefSeq |
NM_001216.1, NP_001207.1 |
| RefSeq Size |
1552 |
| RefSeq ORF |
1380 |
| Locus ID |
768 |
| Cytogenetics |
9p13.3 |
| Protein Families |
Druggable Genome, Transmembrane |
| Protein Pathways |
Nitrogen metabolism |
| Gene Summary |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014] |
Информация для заказа| Область использования: | Производство: | OriGene | | Метод: | | | Объем: | 10 ug | | Кат. номер: | RG204839 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: Carbonic Anhydrase IX (CA9) (NM_001216) Human Tagged ORF Clone.
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