Интерлейкин 6

IL-6, 96

The mouse IL-6 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of mouse IL-6.

The mouse IL-6 ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Interleukin-6 (IL-6) is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis and may play a central role in host defense mechanisms.

IL-6 is usually not produced constitutively by normal cells, but its expression is readily induced by a variety of cytokines, lipopolysaccharide or viral infections.

IL-6 is a pleiotropic cytokine produced by a variety of cells. It acts on a wide range of tissues, exerting growth-induction, growth-inhibition, and differentiation respectively, depending on the nature of the target cells.

IL-6 is involved in

- the induction of B-cell differentiation,

- the induction of acute phase proteins in liver cells,

- growth promotion of myeloma/plasmacytoma/hybridoma cells,

- induction of IL-2 and IL-2 receptor expression,

- proliferation and differentiation of T cells,

- inhibition of cell growth of certain myeloid leukemic cell lines and induction of their differentiation to macrophages,

- enhancement of IL-3-induced multipotential colony cell formation in hematopoietic stem cells and induction of maturation of megakaryocytes as a thrombopoietic factor,

- induction of mesangial cell growth,

- induction of neural differentiation of PC 12 cells and

- induction of keratinocyte growth

The abnormal production of IL-6 was first suggested to be related to polyclonal B-cell activation with autoantibody production in patients with cardiac myxoma. Since then, IL-6 has been suggested to be involved in the pathogenesis of a variety of diseases. Measurement of IL-6 levels in serum and other body fluids thus provides more detailed insights into various pathological situations.

Информация для заказа

Область использования: Прочие ИФА наборы для животных Цитокины, хемокины	Производство:	Bender Medsystems
	Метод:	ELISA
	Объем:	96
	Кат. номер:	BMS603
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Интерлейкин 6 / IL-6, 96. Примечание: Enzyme-linked immunosorbent assay for quantitative detection of mouse IL-6.