Моноклональные кроличьи антитела к Рецепторам Эстрогена

Estrogen Receptor (SP1)

Recognizes a protein of 67kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Host Species: Rabbit

Clone: SP1

Isotype: IgG

Species Reactivity: Human, Mouse and Hamster. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor

Molecular Weight: 67kDa

Positive Control: Breast CA, MCF-7 cells

Cellular Localization: Nuclear

Clone SP1 is excellent for staining of formal/paraffin with no special pretreatment.

Storage Conditions: 4°C, Do Not Freeze

Recommended for:

Immunohistochemistry (Formalin/paraffin)
Western Blotting
Immunofluorescence (Not verified)
Flow Cytometery (Not verified)

Спецификация

Клон	SP1
Обработка	low pH 6
Разведение	1:400
Время инкубации	20 минут
Регистрационное удостоверения и пункт РУ	ФСЗ 2010/07400, пункт 13

Информация для заказа

Область использования: Моноклональные антитела (кроличьи)	Производство:	Thermo Fisher Scientific
	Метод:	Иммуногистохимия
	Объем:	1.0ml
	Кат. номер:	RM-9101-S
Цена (с НДС 10%):	по запросу	В корзину
Наименование: Моноклональные кроличьи антитела к Рецепторам Эстрогена / Estrogen Receptor (SP1). Примечание: Клон: SP1