c-erbB2 / HER-2 / neu

HER2 gene encodes a transmembrane glycoprotein with tyrosine kinase activity. It is closely related in structure to the epidermal growth factor receptor c-erbB-3/HER3/neu oncoprotein. The protein is detectable in a subset of breast and other carcinomas (urinary bladder, stomach, lung, endometrium and ovary). In the case of breast cancer, over expression determined by immunohistochemistry has been shown to be associated with poor prognosis and an indication to initiate trastuzumab/herceptin therapy.

Host Species: Rabbit

Clone: EP1045Y

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: A synthetic peptide corresponding to the c-terminus of human Her2

Molecular Weight: 185kDa

Positive Control: Breast carcinomas

Cellular Localization: Cell membrane

Storage Conditions: Store vial at 4°C. When stored at 2-8°C, this antibody is stable for 24 months.

Recommended for:

Immunohistochemistry (Formalin/paraffin)

†USA: ASR; Int'l: IVD

Информация для заказа

Область использования: Моноклональные антитела (кроличьи)	Производство:	Thermo Fisher Scientific
	Метод:	Иммуногистохимия
	Объем:	1.0ml
	Кат. номер:	RM-2112-S
Цена (с НДС 20%):	по запросу	В корзину
Наименование: c-erbB2 / HER-2 / neu . Примечание: Клон: EP1045Y