Антитела моноклональные мышиные IgG1 к Hepatocyte Specific Antigen (OCH1E5)Hepatocyte Specific Antigen Antibody (OCH1E5) is a mouse monoclonal IgG1
- Hepatocyte Specific Antigen Antibody (OCH1E5) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against liver extract of human origin
- recommended for detection of an uncharacterized antigen present in both adults and fetal normal hepatocytes to produce a distinct granular cytoplasmic staining. This antibody stains the majority of hepatocellular carcinomas of human origin by IF and IHC(P)
Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or Hep Par 1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for diagnosing hepatocellular carcinomas (HCC) in humans and dogs and distinguishing them from metastatic carcinomas and cholangiocarcinomas. Strong expression of the Hepatocyte Specific Antigen correlates with smaller tumors and longer patient survival. HCCs occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. A very small percentage of HCCs do not contain the Hepatocyte Specific Antigen, and this may be associated with an alternative mechanism of hepatocarcinogenesis in its early stages. To a lesser extent, the Hepatocyte Specific Antigen is also found in gastric carcinomas as well as a few other nonhepatic tumors. Информация для заказаОбласть использования: | Производство: | Santa Cruz | Метод: | | Объем: | 200 мкг/мл | Кат. номер: | sc-58693 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Антитела моноклональные мышиные IgG1 к Hepatocyte Specific Antigen (OCH1E5) / Hepatocyte Specific Antigen Antibody (OCH1E5) is a mouse monoclonal IgG1. Примечание: SQ Category: Primary Antibodies, Species: human, Host Origin: human, Applications: IF, IHC(P), UNSPSC: 12352203, datasheet |
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