Антитела Alexa Fluor® 647 anti-NRF2 Antibody

Alexa Fluor® 647 anti-NRF2 Antibody

NRF2 is a transcription factor that plays a critical role in inducing expression of genes required for oxidative stress defense and stress balance. It does so by binding to antioxidant response elements (AREs), which are located upstream of target genes. NRF2 is degraded by ubiquitination of KEAP1 E3 ligase. In a clinical setting, NRF2 is frequently activated in many types of cancers; it drives metabolic adaptation and survival in ROS-rich tumor microenvironments.

CloneW19086B (See other available formats)R

egulatory StatusRUO

Other NamesErythroid 2 Like 2, NF-E2-Related Factor 2, HEBP1, IMDDHH

IsotypeRat IgG2a, κ

Информация для заказа

Область использования: Антитела BioLegend	Производство:	Biolegend
	Метод:
	Объем:	100 tests
	Кат. номер:	939206
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Антитела Alexa Fluor® 647 anti-NRF2 Antibody / Alexa Fluor® 647 anti-NRF2 Antibody. Примечание: