Кроличьи поликлональные антитела к десмину (H-76)Desmin Antibody (H-76) is a rabbit polyclonal IgG
- Desmin Antibody (H-76) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope corresponding to amino acids 15-90 mapping near the N-terminus of desmin of human origin
- recommended for detection of desmin of mouse, rat and human origin WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine, bovine and porcine
- See 20 citations for DesminAntibody (H-76)
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain å-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Desmin makes up attachments between the terminal Z-disc and membrane-associated proteins to form a force-transmitting system. Mutations in the gene encoding for Desmin are associated with adult-onset skeletal myopathy, sporadic disease and mild cardiac involvement. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-14026 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Кроличьи поликлональные антитела к десмину (H-76) / Desmin Antibody (H-76) is a rabbit polyclonal IgG .
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
datasheet |
|
