MMP-3 Antibody (1B4) is a mouse monoclonal IgG1
- MMP-3 Antibody (1B4) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against amino acids 317-327 of MMP-3 of human origin
- recommended for detection of MMP-3 of human origin by WB, IP, IF and IHC(P)
- See 14 citations for MMP-3 Antibody (1B4)
 The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, -2 and -3 respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-21732 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: MMP-3 Antibody (1B4) is a mouse monoclonal IgG1.
Примечание: SQ Category: Primary Antibodies,
Species: human,
Host Origin: human,
Applications: WB, IP, IF, IHC(P),
UNSPSC: 12352203,
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