DC-SIGN Antibody (1B10) FITC is a mouse monoclonal IgG2a
- DC-SIGN Antibody (1B10) is a mouse monoclonal IgG2a provided at 200 µg/ml
- recommended for detection of DC-SIGN of human origin by WB, IF, IHC(P) and FCM
- fluorescein (sc-23926 FITC) and phycoerythrin (sc-23926 PE) conjugates for FCM, 100 tests
- See 3 citations for DC-SIGN Antibody (1B10)
Dendritic cells (DCs) are antigen-presenting immune system cells that are present on peripheral mucosal tissues and migrate to lymphoid tissues. DC-SIGN (DC-specific ICAM-3 grabbing nonintegrin) is a type II membrane protein that is exclusively expressed by DCs. DC-SIGN, also designated CD209, binds to ICAM-3 to mediate the initial interaction between DCs and resting T cells through the immunological synapse. The DCs that are present in the initial sites of HIV-1 infection capture HIV-1 through DC-SIGN, which then facilitates the migration of DCs to areas of T cell-rich secondary lymphoid organs, where it promotes efficient trans HIV-1 infection of those T cells. DC-SIGN functions to transport HIV-1 from exposed mucosal surfaces to a lymphoid compartment. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 100 tests in 2 ml | | Кат. номер: | sc-23926 FITC | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: DC-SIGN Antibody (1B10) FITC is a mouse monoclonal IgG2a .
Примечание: SQ Category: Primary Antibody Conjugates,
Species: ,
Host Origin: ,
Applications: WB, IF, IHC(P), FCM,
UNSPSC: 12352203,
datasheet |
|
