| Объем | 100 мкг |
| Синонимы | Proteasome subunit alpha type-7 (EC 3.4.25.1) (Proteasome subunit RC6-1) (Proteasome subunit XAPC7), PSMA7, HSPC |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O14818 |
| Иммуноген | Recombinant Human Proteasome subunit alpha type-7 protein (5-232AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Proteasome subunit alpha type-7 protein |
| Области исследований | Cell biology, Immunology, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PSMA7 antibody at 2µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 21, 17 kDa
Observed band size: 28 kDa
 |
Western blot
All lanes: PSMA7 antibody at 1.6 µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Mouse liver tissue
Lane 3: Mouse kidney tissue
Lane 4: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 28, 21, 17 kDa
Observed band size: 28 kDa
 |
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA01335A0Rb at dilution of 1:100
 |
Immunofluorescent analysis of Hela cells using CSB-PA01335A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
 |
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA01335A0Rb at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA01335A0Rb at dilution of 1:100
 |
| | |
Наименование: Антитела Rabbit anti-human Proteasome subunit alpha type-7 polyclonal Antibody / Rabbit anti-human Proteasome subunit alpha type-7 polyclonal Antibody.