Антитела Rabbit anti-human Kininogen-1 polyclonal Antibody;Biotin conjugated

Rabbit anti-human Kininogen-1 polyclonal Antibody;Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain, T-kinin (Ile-Ser-Bradykinin), Bradykinin (Kallidin I), Lysyl-bradykinin (Kallidin II), Kininogen-1 light chain, Low molecular weight growth-promoting factor], KNG1, BDK KNG
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P01042
Иммуноген	Recombinant Human Kininogen-1 protein (390-644AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA, IHC, Recommended dilution: IHC:1:20-1:200
Примечание	Kininogens are inhibitors of thiol proteases, (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII, (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes, (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action), (5) LMW-kininogen inhibits the aggregation of thrombocytes, (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Kininogen-1 protein
Области исследований	Cardiovascular, Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA14647D0Rb at dilution of 1:100

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкг
	Кат. номер:	CSB-PA14647D0Rb
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Антитела Rabbit anti-human Kininogen-1 polyclonal Antibody;Biotin conjugated / Rabbit anti-human Kininogen-1 polyclonal Antibody;Biotin conjugated. Примечание: дополнительная информация (на английском языке).