| Объем | 100 мкг |
| Синонимы | Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1), AATF, CHE1 DED |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NY61 |
| Иммуноген | Recombinant Human Protein AATF protein (6-294AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Protein AATF protein |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: Антитела Rabbit anti-human Protein AATF polyclonal Antibody;Biotin conjugated / Rabbit anti-human Protein AATF polyclonal Antibody;Biotin conjugated.