| Объем | 100 мкг |
| Синонимы | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein), SYNCRIP, HNRPQ NSAP1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O60506 |
| Иммуноген | Recombinant Human Heterogeneous nuclear ribonucleoprotein Q protein (2-191AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Heterogeneous nuclear ribonucleoprotein Q protein |
| Области исследований | Epigenetics and Nuclear Signaling, Microbiology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Heterogeneous nuclear ribonucleoprotein Q antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 70, 66, 63, 59, 47 kDa
Observed band size: 70, 36 kDa
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Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA03334A0Rb at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA03334A0Rb at dilution of 1:100
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Наименование: Антитела Rabbit anti-human Heterogeneous nuclear ribonucleoprotein Q polyclonal Antibody / Rabbit anti-human Heterogeneous nuclear ribonucleoprotein Q polyclonal Antibody.