Антитела Rabbit anti-human Tumor necrosis factor receptor superfamily member 10D polyclonal Antibody;Biotin conjugated

Rabbit anti-human Tumor necrosis factor receptor superfamily member 10D polyclonal Antibody;Biotin conjugated

Immunogen: Recombinant human Tumor necrosis factor receptor superfamily member 10D protein
Raised in: Rabbit
Species Reactivity: Human
Tested applications: ELISA, WB, IHC
Application notes:
Relevance: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to Ref.1, it cannot but according to Ref.2, it can induce the NF-kappa-B pathway.
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: Biotin conjugated
Stroage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Stroage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
References: [1] "A novel receptor for Apo2L/TRAIL contains a truncated death domain."Marsters S.A., Sheridan J.P., Pitti R.M., Huang A., Skubatch M., Baldwin D., Yuan J., Gurney A., Goddard A.D., Godowski P., Ashkenazi A.Curr. Biol. 7:1003-1006(1997) [2] "The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain."Degli-Esposti M.A., Dougall W.C., Smolak P.J., Waugh J.Y., Smith C.A., Goodwin R.G.Immunity 7:813-820(1997) [3] "TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling."Pan G., Ni J., Yu G.-L., Wei Y.-F., Dixit V.M.FEBS Lett. 424:41-45(1998)
Images:
Alias : UNQ251/PRO288,DCR2, TRAILR4, TRUNDD,TNFRSF10D,Decoy receptor 2,DcR2,TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor 4,TRAIL-R4,TRAIL receptor with a truncated death domain,CD_antigen=CD264.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкг
	Кат. номер:	CSB-PA08207D0Rb
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Антитела Rabbit anti-human Tumor necrosis factor receptor superfamily member 10D polyclonal Antibody;Biotin conjugated / Rabbit anti-human Tumor necrosis factor receptor superfamily member 10D polyclonal Antibody;Biotin conjugated. Примечание: дополнительная информация (на английском языке).