Антитела Rabbit anti-human Myoglobin polyclonal Antibody,Biotin conjugated
Rabbit anti-human Myoglobin polyclonal Antibody,Biotin conjugated
Immunogen: Recombinant Human Myoglobin protein
Raised in: Rabbit
Species Reactivity: Human, Mouse, Rat
Tested applications: ELISA, WB, IHC
Application notes:
Relevance: Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
Clonality: Polyclonal
Isotype: IgG
Purity: CA-AS
Conjugate: Biotin
Stroage Buffer: PBS
Form: Liquid
Stroage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
References: [1] "Organization of the human myoglobin gene."Weller P., Jeffreys A.J., Wilson V., Blanchetot A.EMBO J. 3:439-446(1984) [2] "Cloning of the human myoglobin gene."Akaboshi E.Gene 33:241-249(1985) [3] "A genome annotation-driven approach to cloning the human ORFeome." Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I.Genome Biol. 5:R84.1-R84.11(2004)
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Информация для заказа
Область использования: | Производство: | Cusabio |
Метод: | |
Объем: | 100 мкг |
Кат. номер: | CSB-PA07914D0Rb |
Цена (с НДС 20%): | по запросу | В корзину |
Наименование: Антитела Rabbit anti-human Myoglobin polyclonal Antibody,Biotin conjugated / Rabbit anti-human Myoglobin polyclonal Antibody,Biotin conjugated. Примечание: дополнительная информация (на английском языке). |