Rabbit Anti Human ATF4 PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | ATF4,CREB-2,CREB2,TAXREB67,TXREB | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P18848 | Иммуноген | Recombinant protein of human ATF4 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from mouse craniofacial and mouse gastrocnemius, using ATF4 antibody.
| Immunohistochemistry of paraffin-embedded Breast cancer using ATF4 Antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA002272KA01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human ATF4 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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