Rabbit Anti Human SGK1 PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | SGK, SGK1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O00141 | Иммуноген | Recombinant protein of human SGK1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation. SGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. SGK is negatively regulated by ubiquitination and proteasome degradation.The MAP kinase family member BMK1 interacts with and activates SGK by phosphorylation at serine 78. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Developmental biology,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of HepG2 cell lysate using SGK1 antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA021189KA01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human SGK1 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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