Rabbit Anti Human SUMO1 PolyClonal AntibodyСпецификация| Объем | 100 мкл (100 мкг) | | Синонимы | SUMO1,DAP1,GMP1,OFC10,PIC1,SENP2,SMT3,SMT3C,SMT3H3, UBL1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P63165 | | Иммуноген | A synthetic peptide of human SUMO-1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, ICC, IP, FC,WB:1:500-1:2000, IHC:1:20-1:200, ICC:1:50-1:200, IP:1:20-1:50, FC:1:20-1:50 | | Примечание | Small ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family. The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to ubiquitination. This post-translational modification is a reversible, multi-step process that is initiated by cleaving a precursor protein to a mature protein. Mature SUMO-1, -2 or -3 is then linked to the activating enzyme E1, conjugated to E2 and in conjunction with E3, SUMO-1, -2 or -3 is ligated to the target protein. Ubiquitin and the individual SUMO family members are all targeted to different proteins with diverse biological functions. Ubiquitin predominantly regulates degradation of its target. In contrast, SUMO-1 is conjugated to RanGAP, PML, p53 and IκB-alpha to regulate nuclear trafficking, formation of subnuclear structures, regulation of transcriptional activity and protein stability. SUMO-2/-3 forms poly-(SUMO) chains, is conjugated to topoisomerase II and APP, regulates chromosomal segregation and cellular responses to environmental stress, and plays a role in the progression of Alzheimer disease. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Affinity purification | | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of NIH3T3 cell lysate using SUMO-1 antibody.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | | | Объем: | 100 мкл (100 мкг) | | Кат. номер: | CSB-PA022948KA01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Rabbit Anti Human SUMO1 PolyClonal Antibody.
Примечание: дополнительная информация (на английском языке). |
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