Rabbit Anti Human CHUK PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O15111 | Иммуноген | A synthetic peptide of human CHUK | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | The NF-κB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IκB proteins. Most agents that activate NF-κB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IκB. The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits. IKKalpha and IKKbeta serve as the catalytic subunits of the kinase and IKKgamma serves as the regulatory subunit . Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKbeta (Ser176 and Ser180 in IKKalpha), which causes conformational changes, resulting in kinase activation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Cancer,Cardiovascular,Cell biology,Immunology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts of various cell lines, using CHUK antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA005420KA01HU | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: Rabbit Anti Human CHUK PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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