Rabbit Anti Human TNFRSF6B PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | TNFRSF6B,DCR3, TR6 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O95407 | Иммуноген | Recombinant protein of human TNFRSF6B | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems. The receptors are activated by a family of cytokines that include TNF, FasL, and TRAIL. They are characterized by a highly conserved extracellular region containing cysteine-rich repeats and a conserved intracellular region of about 80 amino acids termed the death domain (DD). The DD is important for transducing the death signal by recruiting other DD containing adaptor proteins (FADD, TRADD, RIP) to the death-inducing signaling complex (DISC), resulting in activation of caspases.Death receptor signaling is also controlled by a family of decoy receptors (DcR1, DcR2 and DcR3) which lack a cytoplasmic DD and inhibit death receptor-mediated apoptosis by competing for ligand. Expression of decoy receptors provide a mechanism for certain types of cancer to regulate apoptosis and can contribute to chemosensitivity. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Cancer,Cell biology,Immunology | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of 293 cell lysate using TNFRSF6B antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA023982KA01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human TNFRSF6B PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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