Rabbit Anti Human CLDN1 PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | CLDN1,CLD1, ILVASC, SEMP1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O95832 | Иммуноген | Recombinant protein of human CLDN1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | Tight junctions, or zonula occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane proteins between the apical and the basolateral cell surfaces. Tight junctions are composed of claudin and occludin proteins, which join the junctions to the cytoskeleton. The claudin family is composed of 23 integral membrane proteins, and their expression, which varies among tissue types, may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer. Claudin-1 is expressed primarily in keratinocytes and normal mammary epithelial cells, but is absent or reduced in breast carcinomas and breast cancer cell lines. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts of Jurkat cell lines, using CLDN1 antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA005490KA01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human CLDN1 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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