Rabbit Anti Human LTA PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | LT, TNFB, TNFSF1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P01374 | Иммуноген | Recombinant protein of human LTA | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | Lymphotoxin-alpha (LT-alpha), also known as TNF–beta, is a member of the TNF superfamily of proteins. NK cells, T cells, B cells, and lymphoid tissue-inducer cells express LT-alpha. LT-alpha can be secreted as a soluble homotrimer or form membrane bound heterotrimers with lymphotoxin-beta (LT alpha1beta2 or LT alpha2beta1) which can be cleaved from the cell surface by matrix metalloproteases. Soluble LT-alpha binds to and signals through TNFR1/TNFR2, activating the canonical NF-κB pathway. In contrast, LT alpha1beta2 heterodimers bind to the LTbetaR receptor and activate the noncanonical NF-κB pathway. As a result, LT-alpha and TNF-alpha have overlapping functions. Soluble LT-alpha and LT alpha1beta2 play key roles in lymphangiogenesis. The LT alpha1beta2/LTbetaR axis is essential for the development of lymphoid tissue. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Cancer,Immunology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts of human spleen cell lines, using LTA antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA013218KA01HU | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: Rabbit Anti Human LTA PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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