Rabbit Anti Human NOD1 PolyClonal Antibody

Спецификация

Объем	100 мкл (100 мкг)
Синонимы	NOD1,CARD4,CLR7.1,NLRC1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q9Y239
Иммуноген	Recombinant protein of human NOD1
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200
Примечание	Nod1/CARD4 is a cytosolic protein structually related to Apaf-1 and plant drug-resistance proteins that has been implicated in apoptosis and inflammatory responses to certain pathogenic bacteria. It contains an amino-terminal caspase recruitment domain (CARD) that is linked to a central nucleotide-binding domain (NBD, also known as a NOD domain) and is followed by carboxy-terminal leucine-rich repeats (LRR). Like Apaf-1, Nod1 induces apoptosis by a CARD/NBD-dependent activation of caspase-9. The primary function of Nod1 is thought to be as a sensor for certain pathogenic microbes and triggering inflammatory responses including the activation of NF-κB and JNK pathways. The LRR of Nod1 appears to be involved in recognition of microbial components and the CARD domain induces NF-κB activation in cooperation with the CARD containing kinase, RICK/RIP2/CARDIAK. Mutations in Nod1 have been linked increased susceptibility to asthma and inflammatory bowel disease.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Affinity purification
Области исследований	Cell biology
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of Mouse bladder cell lysate using NOD1 antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкл (100 мкг)
	Кат. номер:	CSB-PA015914KA01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Rabbit Anti Human NOD1 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке).