Rabbit Anti Human GNAZ PolyClonal Antibody

Спецификация

Объем	100 мкл (100 мкг)
Синонимы	Gz-alpha, G(x) alpha chain, Guanine nucleotide-binding protein G(z) subunit alpha, GNAZ
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P19086
Иммуноген	Recombinant protein of human GNAZ
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200
Примечание	Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of alpha, beta and gamma subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Galpha subunits have been classified into four families, Galpha(s), Galpha(i/o), Galpha(q) and Galpha(12), based on structural and functional similarities. Phosphorylation of Tyr356 of Galpha(q)/Galpha(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Galpha with receptors and abolishes ligand-induced IP3 formation.Galpha(z) stands out from other G proteins because it lacks an ADP-ribosylation consensus site for pertussis toxin, giving it a possible role in signal transduction pathways resistant to the toxin, such as phospholipase C. Galpha(z) is phosphorylated and activated by protein kinase C (PKC) at Ser27.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Affinity purification
Области исследований	Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of HepG2 cell lysate using GNA2antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкл (100 мкг)
	Кат. номер:	CSB-PA009601KA01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Rabbit Anti Human GNAZ PolyClonal Antibody. Примечание: дополнительная информация (на английском языке).