Rabbit Anti Human IL10 PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF, Interleukin-10, Cytokine synthesis inhibitory factor | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P22301 | Иммуноген | Recombinant protein of human IL10 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | IL-10 is an anti-inflammatory cytokine that is produced by T cells, NK cells and macrophages. IL-10 initiates signal transduction by binding to a cell surface receptor complex consisting of IL-10 RI and IL-10 RII. Binding of IL-10 leads to the activation of Jak1 and Tyk2, which phosphorylates Stat-3. The anti-inflammatory activity of IL-10 is due to its ability to block signaling through other cytokine receptors, notably IFNgamma receptor, by upregulating expression of SOCS-1. In addition, IL-10 promotes T cell tolerance by inhibiting tyrosine phosphorylation of CD28. IL-10 is an important negative regulator of the immune response, which allows for maintenance of pregnancy. In contrast, increased IL-10 levels contribute to persistent Leishmania major infections. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Cancer,Immunology | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts of various cell lines, using IL10 antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA011580KA01HU-100 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human IL10 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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