Rabbit Anti Human ITGAV PolyClonal AntibodyСпецификацияОбъем | 100 мкл (100 мкг) | Синонимы | ITGAV, CD51, MSK8, VNRA, VTNR | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P06756 | Иммуноген | A synthetic peptide of human ITGAV | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | Integrins are alpha/beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several alphaV subfamily members, including alphaVbeta3, alphaVbeta5, alphaVbeta1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis. Therefore, interest has focused on alphaV integrin as a key therapeutic target in the treatment of cancer. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity purification | Области исследований | Cancer,Cardiovascular,Microbiology,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts of A549 cell lines, using ITGAV antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | | Объем: | 100 мкл (100 мкг) | Кат. номер: | CSB-PA011877KA01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Rabbit Anti Human ITGAV PolyClonal Antibody. Примечание: дополнительная информация (на английском языке). |
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