Объем | 100 мкл |
Синонимы | BRODL, bromodomain and WD repeat domain containing 3, FLJ38568, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P11142 |
Иммуноген | Synthesized peptide derived from internal of human HSPA8. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.<br/><br/>Muraki T., Mol. Pharmacol. 58:1257-1263(2000).<br/>Quadroni M., Submitted (MAR-2009).<br/>Keith W.N., Submitted (JAN-2010).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEC, K562, Jurkat and HeLa cells, using HSPA8 antibody.
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