ABCG2 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | ATP-binding cassette sub-family G member 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9UNQ0 | Иммуноген | Synthetic peptide of human ABCG2 | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 | Примечание | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Tags & Cell Markers,Metabolism,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA988836(ABCG2 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 10%SDS-PAGE, Lysate: 20 ?g, Lane: HepG2 cells, Primary antibody: CSB-PA988836(ABCG2 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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