ABCG5 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | ATP-binding cassette, sub-family G (WHITE), member 5 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9H222 | Иммуноген | Synthetic peptide of human ABCG5 | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 | Примечание | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA935474(ABCG5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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