ACTN2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | actinin, alpha 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P35609 | Иммуноген | Synthetic peptide of human ACTN2 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100 | Примечание | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cardiovascular,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA828857(ACTN2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Mouse heart tissue, Mouse muscle tissue, Primary antibody: CSB-PA828857(ACTN2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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