Объем | 50 мкл |
Синонимы | Activin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7), ACVR1C, ALK7 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8NER5 |
Иммуноген | Recombinant Human Activin receptor type-1C protein (22-113AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
Примечание | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Epigenetics and Nuclear Signaling, Cancer, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: ACVR1C antibody at 4µg/ml
Lane 1: Mouse brain tissue
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 38, 47, 50 kDa
Observed band size: 55 kDa
 |
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA854112ESR1HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA854112ESR1HU at dilution of 1:100
 |
| |