Объем | 100 мкл |
Синонимы | activin A receptor, type IC |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8NER5 |
Иммуноген | Fusion protein of human ACVR1C |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:15-1:50 |
Примечание | ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA961708(ACVR1C Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA961708(ACVR1C Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ?200)
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