ACVR1C AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Activin receptor type-1C, EC 2.7.11.30, ACTR-IC, Activin receptor-like kinase 7, ALK-7 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q8NER5 | | Иммуноген | Synthesized peptide derived from internal of human ACTR-1C. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 | | Примечание | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.<br/><br/>Bondestam J., Cytogenet. Cell Genet. 95:157-162(2001).<br/>Roberts H.J., Biol. Reprod. 68:1719-1726(2003).<br/>Hillier L.W., Nature 434:724-731(2005).<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ACTR-1C antibody.
 | Immunofluorescence analysis of COS-7 cells, using ACTR-1C antibody.
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Наименование: ACVR1C Antibody.