| Объем | 100 мкл |
| Синонимы | ADRBK1, adrenergic, beta, receptor kinase 1, ARBK1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P25098 |
| Иммуноген | Synthesized peptide derived from N-terminal of human ADRBK1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.<br/><br/>Benovic J.L., FEBS Lett. 283:122-126(1991).<br/>Chuang T.T., J. Biol. Chem. 267:6886-6892(1992).<br/>Penn R.B., J. Biol. Chem. 269:14924-14930(1994).<br/><br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from NIH-3T3 cells, using GRK2 (Ab-86) antibody.
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Western blot analysis of extracts from cos-7 cells (Lane 2), using GRK2 (Ab-86) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: ADRBK1 (Ab-86) Antibody.