Объем | 100 мкл |
Синонимы | AlkB, alkylation repair homolog 2 (E. coli) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q6NS38 |
Иммуноген | Fusion protein of human ALKBH2 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Примечание | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-3: Human fetal liver tissue, Human seminoma tissue, RAW264.7 cells, Primary antibody: CSB-PA031205(ALKBH2 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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