ALPL AntibodyСпецификацияОбъем | 50 мкл | Синонимы | Alkaline phosphatase | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P05186 | Иммуноген | Fusion protein of human ALPL | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, IHC,ELISA:1:500-1:2000, IHC:1:25-1:100 | Примечание | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cell biology,Tags & Cell Markers,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA228295(ALPL Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
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