| Объем | 50 мкг |
| Синонимы | Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein), ACD, PIP1 PTOP TINT1 TPP1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96AP0 |
| Иммуноген | Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | FITC |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Adrenocortical dysplasia protein homolog |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: ACD Antibody, FITC conjugated.