| Объем | 100 мкл |
| Синонимы | Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (AFB1 aldehyde reductase 1) (AFB1-AR 1) (Aldoketoreductase 7) (Succinic semialdehyde reductase) (SSA reductase), AKR7A2, AFAR AFAR1 AKR7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O43488 |
| Иммуноген | Recombinant Human Aflatoxin B1 aldehyde reductase member 2 protein (100-359AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Aflatoxin B1 aldehyde reductase member 2 |
| Области исследований | Neuroscience, Cancer, Metabolism, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: AKR7A2 antibody at 0.88µg/ml
Lane 1: Mouse small intestine tissue
Lane 2: Mouse liver tissue
Lane 3: Mouse gonadal tissue
Lane 4: A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 40 kDa
Observed band size: 40 kDa
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001550ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA001550ESR1HU at dilution of 1:100
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Наименование: AKR7A2 Antibody.