| Объем | 50 мкг |
| Code NO# | 5A11E5 |
| Синонимы | Amyloid Beta (A4) Precursor Protein,ABPP,APP,Beta-Amyloid Peptide |
| Тип антител | Monoclonal Antibody |
| Видовая специфичность | Human |
| Uniport ID | P05067 |
| Иммуноген | Recombinant Human APP Protein |
| Источник | mouse |
| Видовая специфичность 1 | Human,Mouse |
| Перекрестная реактивность | specific for human APP denatured and native forms. |
| Применение | ELISA,WB,IHC,IF,Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,IF:1:50-1:200 |
| Примечание | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. |
| Метод очистки | >95%,Protein G purified |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Области исследований | Neuroscience |
| Станица на сайте производителя | ссылка |
Western blot
All lanes :Amyloid beta A4 antibody at 1µg/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse kidney tissue
Lane 3: Mouse lung tissue
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size : 30,35,72,80 kDa
Observed band size : 30,35,72 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-MA0019501A0m at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-MA0019501A0m at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-MA0019501A0m at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Immunofluorescent analysis of HepG2 cells using CSB-MA0019501A0m at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: APP Monoclonal Antibody.