| Объем | 100 мкл |
| Синонимы | Angiopoietin-related protein 4 (Angiopoietin-like protein 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP), ANGPTL4, ARP4 HFARP PGAR |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9BY76 |
| Иммуноген | Recombinant Human Angiopoietin-related protein 4 protein (26-406AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cancer, Cardiovascular, Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Angiopoietin-related protein 4 antibody at 2µg/ml + Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 41, 27 kDa
Observed band size: 46 kDa
 |
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA866314ESR2HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA866314ESR2HU at dilution of 1:100
 |
| | |
Наименование: ANGPTL4 Antibody.