Объем | 100 мкл |
Синонимы | ANAPC5, Anaphase-promoting complex subunit 5, ANC5, Similar to anaphase-promoting complex subunit 5, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UJX4 |
Иммуноген | Synthesized peptide derived from internal of human ANAPC5. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<br/><br/>Yu H., Science 279:1219-1222(1998).<br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/>Kraft C., EMBO J. 22:6598-6609(2003).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, Jurkat cells and COLO205 cells, using ANAPC5 antibody.
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