Объем | 50 мкл |
Синонимы | APAF1 interacting protein |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q96GX9 |
Иммуноген | Fusion protein of human APIP |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,ELISA:1:500-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
Примечание | APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA555100(APIP Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 10%SDS-PAGE, Lysate: 60 ?g, Lane: Mouse heart tissue, Primary antibody: CSB-PA555100(APIP Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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