Объем | 50 мкг |
Синонимы | C->U-editing enzyme APOBEC-1 (EC 3.5.4.36) (Apolipoprotein B mRNA-editing enzyme 1) (HEPR) (mRNA(cytosine(6666)) deaminase 1), APOBEC1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P41238 |
Иммуноген | Recombinant Human C->U-editing enzyme APOBEC-1 protein (1-172AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IF, Recommended dilution: IF:1:50-1:200 |
Примечание | Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | C->U-editing enzyme APOBEC-1 |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Immunofluorescence staining of HepG2 cells with CSB-PA001919LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
![](http://www.cusabio.cn/images/antibody/4/CSB-PA001919LA01HU-IF.jpg) |
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