ARF1 Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | ADP-ribosylation factor 1, ARF1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P84077 | Иммуноген | Recombinant Human ADP-ribosylation factor 1 protein (2-181AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | ADP-ribosylation factor 1 | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA00929D0Rb | Цена (с НДС 20%): | по запросу | В корзину | Наименование: ARF1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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