ASH2L AntibodyСпецификацияОбъем | 100 мкл | Синонимы | ASH2, Bre2, ASH2L1, ASH2L2, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9UBL3 | Иммуноген | Peptide sequence around aa.620~624(G-R-R-S-P) derived from Human ASH2L. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. <br/><br/>Wysocka J., Myers M.P., Laherty C.D., Eisenman R.N., Herr W.Genes Dev. 17:896-911(2003)<br/>Patel A., Dharmarajan V., Vought V.E., Cosgrove M.S.J. Biol. Chem. 284:24242-24256(2009) | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Epigenetics and Nuclear Signaling,Cancer | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from HL-60 cells using ASH2L Antibody
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