ARL6IP1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | ADP-ribosylation factor-like 6 interacting protein 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15041 | | Иммуноген | Fusion protein of human ARL6IP1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 | | Примечание | ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA178890(ARL6IP1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
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Наименование: ARL6IP1 Antibody.