Объем | 100 мкл |
Синонимы | Rho guanine nucleotide exchange factor (GEF) 11 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O15085 |
Иммуноген | Synthetic peptide of human ARHGEF11 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Примечание | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA239750(ARHGEF11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA239750(ARHGEF11 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse brain tissue, Primary antibody: CSB-PA239750(ARHGEF11 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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