Объем | 50 мкл |
Синонимы | arrestin, beta 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P49407 |
Иммуноген | Fusion protein of human ARRB1 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Neuroscience,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA830451(ARRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
|
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA830451(ARRB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
|
| |