ARTN AntibodyСпецификацияОбъем | 100 мкл | Синонимы | artemin | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q5T4W7 | Иммуноген | Synthetic peptide of human ARTN | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | Примечание | The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Neuroscience | Ссылка на страницу на сайте производителя | ссылка | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: A431 cells, 231 cells, Primary antibody: CSB-PA097268(ARTN Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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