ATF2 (Ab-73 or 55) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | CREB2, CREBP1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P15336 | Иммуноген | Peptide sequence around aa.71~75 or 53~57 (T-P-T-R-F) derived from Human ATF2. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | Примечание | Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.<br/><br/>Beausoleil S A, et al. (2004) Proc Natl Acad Sci U S A. 101(33): 12130-12135.<br/>Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089.<br/>Gupta S, et al. (1995) Science. 267: 389-393.<br/>Van Dam H, et al. (1995) EMBO J. 14(8): 1798-1811.<br/>Livingstone C, et al. (1995) EMBO J. 14: 1785-1797.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Epigenetics and Nuclear Signaling,Immunology | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from LOVO cells using ATF2(Ab-73 or 55) Antibody and the same antibody preincubated with blocking peptide.
![](http://www.cusabio.cn/images/cb/CSB-PA075264-WB-1.jpg) | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ATF2(Ab-73 or 55) Antibody(left) or the same antibody preincubated with blocking peptide(right).
![](http://www.cusabio.cn/images/cb/CSB-PA075264-IHC-1.jpg) | | |
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